Jornada 1 (5 – 07 Ago.)
| Crystal Palace | 0 – 2 | Arsenal |
| Fulham | 2 – 2 | Liverpool |
| Bournemouth | 2 – 0 | Aston Villa |
| Leeds | 2 – 1 | Wolves |
| Tottenham | 4 – 1 | Southampton |
| Newcastle | 2 – 0 | Nottingham Forest |
| Everton | 0 – 1 | Chelsea |
| Leicester | 2 – 2 | Brentford |
| M. United | 1 – 2 | Brighton |
| West Ham | 0 – 2 | M. City |
Jornada 2 (13 – 15 Ago.)
| Aston Villa | 2 – 1 | Everton |
| Arsenal | 4 – 2 | Leicester |
| Brighton | 0 – 0 | Newcastle |
| M. City | 4 – 0 | Bournemouth |
| Southampton | 2 – 2 | Leeds |
| Wolves | 0 – 0 | Fulham |
| Brentford | 4 – 0 | M. United |
| Nottingham Forest | 1 – 0 | West Ham |
| Chelsea | 2 – 2 | Tottenham |
| Liverpool | 1 – 1 | Crystal Palace |
Jornada 3 (20 – 22 Ago.)
| Tottenham | 1 – 0 | Wolves |
| Crystal Palace | 3 – 1 | Aston Villa |
| Fulham | 3 – 2 | Brentford |
| Leicester | 1 – 2 | Southampton |
| Everton | 1 – 1 | Nottingham Forest |
| Bournemouth | 0 – 3 | Arsenal |
| Leeds | 3 – 0 | Chelsea |
| West Ham | 0 – 2 | Brighton |
| Newcastle | 3 – 3 | M. City |
| M. United | 2 – 1 | Liverpool |
Jornada 4 (27 – 28 Ago.)
| Southampton | 0 – 1 | M. United |
| Brentford | 1 – 1 | Everton |
| Brighton | 1 – 0 | Leeds |
| Chelsea | 2 – 1 | Leicester |
| Liverpool | 9 – 0 | Bournemouth |
| M. City | 4 – 2 | Crystal Palace |
| Arsenal | 2 – 1 | Fulham |
| Aston Villa | 0 – 1 | West Ham |
| Wolves | 1 – 1 | Newcastle |
| Nottingham Forest | 0 – 2 | Tottenham |
Jornada 5 (30 Ago. – 01 Sept.)
| Crystal Palace | 1 – 1 | Brentford |
| Fulham | 2 – 1 | Brighton |
| Southampton | 2 – 1 | Chelsea |
| Leeds | 1 – 1 | Everton |
| Arsenal | 2 – 1 | Aston Villa |
| Bournemouth | 0 – 0 | Wolves |
| M. City | 6 – 0 | Nottingham Forest |
| West Ham | 1 – 1 | Tottenham |
| Liverpool | 2 – 1 | Newcastle |
| Leicester | 0 – 1 | M. United |
Jornada 6 (03 – 04 Sept.)
| Everton | 0 – 0 | Liverpool |
| Brentford | 5 – 2 | Leeds |
| Newcastle | 0 – 0 | Crystal Palace |
| Tottenham | 2 – 1 | Fulham |
| Wolves | 1 – 0 | Southampton |
| Nottingham Forest | 2 – 3 | Bournemouth |
| Aston Villa | 1 – 1 | M. City |
| Brighton | 5 – 2 | Leicester |
| Chelsea | 2 – 1 | West Ham |
| M. United | 3 – 1 | Arsenal |
Jornada 7 (10 – 12 Sept.)
| Fulham | AJORNAT | Chelsea |
| Bournemouth | AJORNAT | Brighton |
| Leicester | AJORNAT | Aston Villa |
| Liverpool | AJORNAT | Wolves |
| Southampton | AJORNAT | Brentford |
| M. City | AJORNAT | Tottenham |
| Arsenal | AJORNAT | Everton |
| West Ham | AJORNAT | Newcastle |
| Crystal Palace | 1 – 1 | M. United |
| Leeds | AJORNAT | Nottingham Forest |
Jornada suspesa per la mort de la reina d’Anglaterra Isabel II (1926-2022)Jornada 8 (16 – 18 Sept.)
| Aston Villa | 1 – 0 | Southampton |
| Nottingham Forest | 2 – 3 | Fulham |
| Wolves | 0 – 3 | M. City |
| Brighton | AJORNAT | Crystal Palace |
| Everton | 1 – 0 | West Ham |
| Newcastle | 1 – 1 | Bournemouth |
| Tottenham | 6 – 2 | Leicester |
| Brentford | 0 – 3 | Arsenal |
| M. United | AJORNAT | Leeds |
| Chelsea | AJORNAT | Liverpool |
Jornada 9 (01 – 03 Oct.)
| Arsenal | 3 – 1 | Tottenham |
| Bournemouth | 0 – 0 | Brentford |
| Crystal Palace | 1 – 2 | Chelsea |
| Fulham | 1 – 4 | Newcastle |
| Liverpool | 3 – 3 | Brighton |
| Southampton | 1 – 2 | Everton |
| West Ham | 2 – 0 | Wolves |
| Leeds | 0 – 0 | Aston Villa |
| M. City | 6 – 3 | M. United |
| Leicester | 4 – 0 | Nottingham Forest |
Jornada 10 (08 – 10 Oct.)
| Bournemouth | 2 – 1 | Leicester |
| Chelsea | 3 – 0 | Wolves |
| M. City | 4 – 0 | Southampton |
| Newcastle | 5 – 1 | Brentford |
| West Ham | 3 – 1 | Fulham |
| Brighton | 0 – 1 | Tottenham |
| Crystal Palace | 2 – 1 | Leeds |
| Arsenal | 3 – 2 | Liverpool |
| Everton | 1 – 2 | M. United |
| Nottingham Forest | 1 – 1 | Aston Villa |
Jornada 11 (14 – 16 Oct.)
| Brentford | 2 – 0 | Brighton |
| Leicester | 0 – 0 | Crystal Palace |
| Fulham | 2 – 2 | Bournemouth |
| Southampton | 1 – 1 | West Ham |
| Wolves | 1 – 0 | Nottingham Forest |
| Tottenham | 2 – 0 | Everton |
| Aston Villa | 0 – 2 | Chelsea |
| Leeds | 0 – 1 | Arsenal |
| M. United | 0 – 0 | Newcastle |
| Liverpool | 1 – 0 | M. City |
Jornada 12 (18 – 20 Oct.)
| Crystal Palace | 2 – 1 | Wolves |
| Brighton | 0 – 0 | Nottingham Forest |
| Bournemouth | 0 – 1 | Southampton |
| Liverpool | 1 – 0 | West Ham |
| Newcastle | 1 – 0 | Everton |
| M. United | 2 – 0 | Tottenham |
| Brentford | 0 – 0 | Chelsea |
| Fulham | 3 – 0 | Aston Villa |
| Leicester | 2 – 0 | Leeds |
| Arsenal | 1 – 3 | M. City |
Jornada 13 (22 – 24 Oct.)
| Nottingham Forest | 1 – 0 | Liverpool |
| Everton | 3 – 0 | Crystal Palace |
| Tottenham | 1 – 2 | Newcastle |
| Aston Villa | 4 – 0 | Brentford |
| Leeds | 2 – 3 | Fulham |
| M. City | 3 – 1 | Brighton |
| Southampton | 1 – 1 | Arsenal |
| Wolves | 0 – 4 | Leicester |
| Chelsea | 1 – 1 | M. United |
| West Ham | 2 – 0 | Bournemouth |
Jornada 14 (29 – 30 Oct.)
| Leicester | 0 – 1 | M. City |
| Bournemouth | 2 – 3 | Tottenham |
| Brentford | 1 – 1 | Wolves |
| Brighton | 4 – 1 | Chelsea |
| Crystal Palace | 1 – 0 | Southampton |
| Newcastle | 4 – 0 | Aston Villa |
| Fulham | 0 – 0 | Everton |
| Liverpool | 1 – 2 | Leeds |
| Arsenal | 5 – 0 | Nottingham Forest |
| M. United | 1 – 0 | West Ham |
Jornada 15 (05 Nov.)
| Aston Villa | 3 – 1 | M. United |
| Chelsea | 0 – 1 | Arsenal |
| Everton | 0 – 2 | Leicester |
| Leeds | 4 – 3 | Bournemouth |
| M. City | 2 – 1 | Fulham |
| Southampton | 1 – 4 | Newcastle |
| Tottenham | 1 – 2 | Liverpool |
| West Ham | 1 – 2 | Crystal Palace |
| Wolves | 2 – 3 | Brighton |
| Nottingham Forest | 2 – 2 | Brentford |
Jornada 16 (12 Nov.)
| Bournemouth | 3 – 0 | Everton |
| Brighton | 1 – 2 | Aston Villa |
| Fulham | 1 – 2 | M. United |
| Liverpool | 3 – 1 | Southampton |
| M. City | 1 – 2 | Brentford |
| Newcastle | 1 – 0 | Chelsea |
| Tottenham | 4 – 3 | Leeds |
| West Ham | 0 – 2 | Leicester |
| Wolves | 0 – 2 | Arsenal |
| Nottingham Forest | 1 – 0 | Crystal Palace |
Jornada 17 (26 Des.)
| Arsenal | 3 – 1 | West Ham |
| Aston Villa | 1 – 3 | Liverpool |
| Brentford | 2 – 2 | Tottenham |
| Chelsea | 2 – 0 | Bournemouth |
| Crystal Palace | 0 – 3 | Fulham |
| Everton | 1 – 2 | Wolves |
| Leeds | 1 – 3 | M. City |
| Leicester | 0 – 3 | Newcastle |
| Southampton | 1 – 3 | Brighton |
| M. United | 3 – 0 | Nottingham Forest |
Jornada 18 (31 Des.)
| Bournemouth | 0 – 2 | Crystal Palace |
| Brighton | 2 – 4 | Arsenal |
| Fulham | 2 – 1 | Southampton |
| Liverpool | 2 – 1 | Leicester |
| M. City | 1 – 1 | Everton |
| Newcastle | 0 – 0 | Leeds |
| Tottenham | 0 – 2 | Aston Villa |
| West Ham | 0 – 2 | Brentford |
| Wolves | 0 – 1 | M. United |
| Nottingham Forest | 1 – 1 | Chelsea |
Jornada 19 (02 Gen.)
| Arsenal | 0 – 0 | Newcastle |
| Aston Villa | 1 – 1 | Wolves |
| Brentford | 3 – 1 | Liverpool |
| Chelsea | 0 – 1 | M. City |
| Crystal Palace | 0 – 4 | Tottenham |
| Everton | 1 – 4 | Brighton |
| Leeds | 2 – 2 | West Ham |
| Leicester | 0 – 1 | Fulham |
| M. United | 3 – 0 | Bournemouth |
| Southampton | 0 – 1 | Nottingham Forest |
Jornada 20 (14 Gen.)
| Aston Villa | 2 – 1 | Leeds |
| Brentford | 2 – 0 | Bournemouth |
| Brighton | 3 – 0 | Liverpool |
| Chelsea | 1 – 0 | Crystal Palace |
| Everton | 1 – 2 | Southampton |
| M. United | 2 – 1 | M. City |
| Newcastle | 1 – 0 | Fulham |
| Tottenham | 0 – 2 | Arsenal |
| Wolves | 1 – 0 | West Ham |
| Nottingham Forest | 2 – 0 | Leicester |
Jornada 21 (21 Gen.)
| Arsenal | 3 – 2 | M. United |
| Crystal Palace | 0 – 0 | Newcastle |
| Fulham | 0 – 1 | Tottenham |
| Leeds | 0 – 0 | Brentford |
| Leicester | 2 – 2 | Brighton |
| Liverpool | 0 – 0 | Chelsea |
| M. City | 3 – 0 | Wolves |
| Southampton | 0 – 1 | Aston Villa |
| West Ham | 2 – 0 | Everton |
| Bournemouth | 1 – 1 | Nottingham Forest |
Jornada 22 (04 Feb.)
| Aston Villa | 2 – 4 | Leicester |
| Brentford | 3 – 0 | Southampton |
| Brighton | 1 – 0 | Bournemouth |
| Chelsea | 0 – 0 | Fulham |
| Everton | 1 – 0 | Arsenal |
| M. United | 2 – 1 | Crystal Palace |
| Newcastle | 1 – 1 | West Ham |
| Tottenham | 1 – 0 | M. City |
| Wolves | 3 – 0 | Liverpool |
| Nottingham Forest | 1 – 0 | Leeds |
Jornada 23 (11 Feb.)
| Arsenal | 1 – 1 | Brentford |
| Bournemouth | 1 – 1 | Newcastle |
| Crystal Palace | 1 – 1 | Brighton |
| Leeds | 0 – 2 | M. United |
| Leicester | 4 – 1 | Tottenham |
| Liverpool | 2 – 0 | Everton |
| M. City | 3 – 1 | Aston Villa |
| Southampton | 1 – 2 | Wolves |
| West Ham | 1 – 1 | Chelsea |
| Fulham | 2 – 0 | Nottingham Forest |
Jornada 24 (18 Feb.)
| Aston Villa | 2 – 4 | Arsenal |
| Brentford | 1 – 1 | Crystal Palace |
| Brighton | 0 – 1 | Fulham |
| Chelsea | 0 – 1 | Southampton |
| Everton | 1 – 0 | Leeds |
| M. United | 3 – 0 | Leicester |
| Newcastle | 0 – 2 | Liverpool |
| Tottenham | 2 – 0 | West Ham |
| Wolves | 0 – 1 | Bournemouth |
| Nottingham Forest | 1 – 1 | M. City |
Jornada 25 (25 Feb.)
| Bournemouth | 1 – 4 | M. City |
| Crystal Palace | 0 – 0 | Liverpool |
| Everton | 0 – 2 | Aston Villa |
| Fulham | 1 – 1 | Wolves |
| Leeds | 1 – 0 | Southampton |
| Leicester | 0 – 1 | Arsenal |
| M. United | S 16:00 | Brentford |
| Newcastle | S 16:00 AJORNAT | Brighton |
| Tottenham | 2 – 0 | Chelsea |
| West Ham | 4 – 0 | Nottingham Forest |
Jornada 26 (04 Mar.)
| Arsenal | 3 – 2 | Bournemouth |
| Aston Villa | 1 – 0 | Crystal Palace |
| Brentford | 3 – 2 | Fulham |
| Brighton | 4 – 0 | West Ham |
| Chelsea | 1 – 0 | Leeds |
| Liverpool | 7 – 0 | M. United |
| M. City | 2 – 0 | Newcastle |
| Southampton | 1 – 0 | Leicester |
| Wolves | 1 – 0 | Tottenham |
| Nottingham Forest | 2 – 2 | Everton |
Jornada 27 (11 Mar.)
| Bournemouth | 1 – 0 | Liverpool |
| Crystal Palace | 0 – 1 | M. City |
| Everton | 1 – 0 | Brentford |
| Fulham | 0 – 3 | Arsenal |
| Leeds | 2 – 2 | Brighton |
| Leicester | 1 – 3 | Chelsea |
| M. United | 3 – 1 | Southampton |
| Newcastle | 2 – 1 | Wolves |
| West Ham | 1 – 1 | Aston Villa |
| Tottenham | 3 – 1 | Nottingham Forest |
Jornada 28 (18 Mar.)
| Arsenal | 4 – 1 | Crystal Palace |
| Aston Villa | 3 – 0 | Bournemouth |
| Brentford | 1 – 1 | Leicester |
| Brighton | 4/5 21:00 | M. United |
| Chelsea | 2 – 2 | Everton |
| Liverpool | 3/5 21:00 | Fulham |
| M. City | 3/5 21:00 | West Ham |
| Southampton | 3 – 3 | Tottenham |
| Wolves | 2 – 4 | Leeds |
| Nottingham Forest | 1 – 2 | Newcastle |
Jornada 29 (01 Abr.)
| Arsenal | 4 – 1 | Leeds |
| Bournemouth | 2 – 1 | Fulham |
| Brighton | 3 – 3 | Brentford |
| Chelsea | 0 – 2 | Aston Villa |
| Crystal Palace | 2 – 1 | Leicester |
| Everton | 1 – 1 | Tottenham |
| M. City | 4 – 1 | Liverpool |
| Newcastle | 2 – 0 | M. United |
| West Ham | 1 – 0 | Southampton |
| Nottingham Forest | 1 – 1 | Wolves |
Jornada 30 (08 Abr.)
| Brentford | 1 – 2 | Newcastle |
| Fulham | 0 – 1 | West Ham |
| Leeds | 1 – 5 | Crystal Palace |
| Leicester | 0 – 1 | Bournemouth |
| Liverpool | 2 – 2 | Arsenal |
| M. United | 2 – 0 | Everton |
| Southampton | 1 – 4 | M. City |
| Tottenham | 2 – 1 | Brighton |
| Wolves | 1 – 0 | Chelsea |
| Aston Villa | 2 – 0 | Nottingham Forest |
Jornada 31 15 Abr.
| Aston Villa | 3 – 0 | Newcastle |
| Chelsea | 1 – 2 | Brighton |
| Everton | 1 – 3 | Fulham |
| Leeds | 1 – 6 | Liverpool |
| M. City | 3 – 1 | Leicester |
| Southampton | 0 – 2 | Crystal Palace |
| Tottenham | 2 – 3 | Bournemouth |
| West Ham | 2 – 2 | Arsenal |
| Wolves | 2 – 0 | Brentford |
| Nottingham Forest | 0 – 2 | M. United |
Jornada 32 (22 Abr.)
| Arsenal | 3 – 3 | Southampton |
| Bournemouth | 0 – 4 | West Ham |
| Brentford | 1 – 1 | Aston Villa |
| Brighton | S 16:00 AJORNAT | M. City |
| Crystal Palace | 0 – 0 | Everton |
| Fulham | 2 – 1 | Leeds |
| Leicester | S 16:00 | Wolves |
| M. United | S 16:00 AJORNAT | Chelsea |
| Newcastle | 6 – 1 | Tottenham |
| Liverpool | 3 – 2 | Nottingham Forest |
Jornada 33 (25 – 26 Abr.)
| Everton | M 20:45 | Newcastle |
| Leeds | 1 – 1 | Leicester |
| Tottenham | M 20:45 | M. United |
| West Ham | 1 – 2 | Liverpool |
| Wolves | 2 – 0 | Crystal Palace |
| Nottingham Forest | 3 – 1 | Brighton |
| Aston Villa | 1 – 0 | Fulham |
| Chelsea | 0 – 2 | Brentford |
| Southampton | X 20:45 | Bournemouth |
| M. City | 4 – 1 | Arsenal |
Jornada 34 (29 Abr.)
| Arsenal | S 16:00 | Chelsea |
| Bournemouth | S 16:00 | Leeds |
| Brighton | S 16:00 | Wolves |
| Crystal Palace | S 16:00 | West Ham |
| Fulham | S 16:00 | M. City |
| Leicester | S 16:00 | Everton |
| Liverpool | S 16:00 | Tottenham |
| M. United | S 16:00 | Aston Villa |
| Newcastle | S 16:00 | Southampton |
| Brentford | S 16:00 | Nottingham Forest |
Jornada 35 (06 Maig.)
| Bournemouth | S 16:00 | Chelsea |
| Brighton | S 16:00 | Everton |
| Fulham | S 16:00 | Leicester |
| Liverpool | S 16:00 | Brentford |
| M. City | S 16:00 | Leeds |
| Newcastle | S 16:00 | Arsenal |
| Tottenham | S 16:00 | Crystal Palace |
| West Ham | S 16:00 | M. United |
| Wolves | S 16:00 | Aston Villa |
| Nottingham Forest | S 16:00 | Southampton |
Jornada 36 (13 Maig.)
| Arsenal | S 16:00 | Brighton |
| Aston Villa | S 16:00 | Tottenham |
| Brentford | S 16:00 | West Ham |
| Crystal Palace | S 16:00 | Bournemouth |
| Everton | S 16:00 | M. City |
| Leeds | S 16:00 | Newcastle |
| Leicester | S 16:00 | Liverpool |
| M. United | S 16:00 | Wolves |
| Southampton | S 16:00 | Fulham |
| Chelsea | S 16:00 | Nottingham Forest |
Jornada 37 (20 Maig.)
| Bournemouth | S 16:00 | M. United |
| Brighton | S 16:00 | Southampton |
| Fulham | S 16:00 | Crystal Palace |
| Liverpool | S 16:00 | Aston Villa |
| M. City | S 16:00 | Chelsea |
| Newcastle | S 16:00 | Leicester |
| Tottenham | S 16:00 | Brentford |
| West Ham | S 16:00 | Leeds |
| Wolves | S 16:00 | Everton |
| Nottingham Forest | S 16:00 | Arsenal |
Jornada 38 (28 Maig.)
| Arsenal | D 17:00 | Wolves |
| Aston Villa | D 17:00 | Brighton |
| Brentford | D 17:00 | M. City |
| Chelsea | D 17:00 | Newcastle |
| Everton | D 17:00 | Bournemouth |
| Leeds | D 17:00 | Tottenham |
| Leicester | D 17:00 | West Ham |
| M. United | D 17:00 | Fulham |
| Southampton | D 17:00 | Liverpool |
| Crystal Palace | D 17:00 | Nottingham Forest |
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